Gene: LEP ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease MGD Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. 7560100 1995
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease MGD Severe pulmonary metastasis in obese and diabetic mice. 16998795 2006
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease MGD Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice. 16394172 2006
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease MGD Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci. 11078464 2000
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Oral administration of Nitraria retusa ethanolic extract enhances hepatic lipid metabolism in db/db mice model 'BKS.Cg-Dock7(m)+/+ Lepr(db/)J' through the modulation of lipogenesis-lipolysis balance. 25086370 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia. 18515891 2008
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. 23839791 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. 9502777 1998
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Congenital leptin deficiency is associated with severe early-onset obesity in humans. 9202122 1997
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study. 25554529 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men. 24042701 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Biologically inactive leptin and early-onset extreme obesity. 25551525 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. 23839791 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human The role of osteopontin in d-galactosamine-induced liver injury in genetically obese mice. 19913045 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study. 25554529 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men. 24042701 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Biologically inactive leptin and early-onset extreme obesity. 25551525 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Leptin-deficient obese (ob/ob) mice and wild-type counterparts (C57/BL6 mice) were exposed to UVB radiation (120 mJ/cm(2)) on alternate days for 1 month. 20122948 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Sequencing of the leptin gene may need to be considered in hyperphagic, severely obese children with detectable levels of circulating leptin. 26186301 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Leptin-deficient obese (ob/ob) mice and wild-type counterparts (C57/BL6 mice) were exposed to UVB radiation (120 mJ/cm(2)) on alternate days for 1 month. 20122948 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight. 17517446 2007
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight. 17517446 2007
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Therapeutic disease CTD_human Insulin depletion leads to adipose-specific cell death in obese but not lean mice. 9826672 1998
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Sequencing of the leptin gene may need to be considered in hyperphagic, severely obese children with detectable levels of circulating leptin. 26186301 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.700 Biomarker disease CTD_human Insulin depletion leads to adipose-specific cell death in obese but not lean mice. 9826672 1998